產(chǎn)品英文名稱：CD4 (L3T4) MicroBeads, mouse
產(chǎn)品中文名稱：美天旎美天旎小鼠CD4 (L3T4)微珠
Miltenyi 美天旎小鼠CD4 (L3T4) MicroBeads微珠產(chǎn)品研究背景：
CD4（L3T4）微珠，為 淋巴和非淋巴組織或外周血單細(xì)胞懸浮液中小鼠T輔助細(xì)胞的正選擇或耗竭而開發(fā)的。該 CD4抗原表達(dá)在大多數(shù)胸腺細(xì)胞和成熟的T輔助細(xì)胞 ，對(duì)NK-T細(xì)胞的一個(gè)子集，并在上一個(gè)亞群水平較低
的樹突狀細(xì)胞。它表達(dá)于胸腺細(xì)胞的約90％， 脾細(xì)胞的25％和淋巴結(jié)細(xì)胞的55％。
美天旎小鼠CD4 (L3T4) MicroBeads微珠產(chǎn)品簡(jiǎn)介：
Components
2 mL CD4 (L3T4) MicroBeads, mouse:
MicroBeads conjugated to monoclonal anti-mouse CD4 antibodies (L3T4; isotype: ratIgG2b;).
Size
For 2×10*9 total cells, up to 200 separations.
Product format
CD4 (L3T4) MicroBeads are supplied as a suspension containing stabilizer and 0.05% sodium azide.
Storage
Store protected from light at 4～8 °C. Do not freeze.The expiration date is indicated on the vial label.
Miltenyi 美天旎小鼠CD4 (L3T4) MicroBeads微珠產(chǎn)品應(yīng)用：
●Isolation of mouse CD4+ T cells from spleen and lymph nodes,brain tissue or bronchoalveolar lavage to study cytokine
●Isolation of CD4-CD8+thymocytes by depleting CD4+cells.
●Isolation of CD4+ T cells for adoptive cell transfer experimentsto study IgE synthesis,the infectious mechanism of mammary tumor viruses or mouse models for diseases such as diabetes,
hepatitis,arthritis or leishmaniasis.secretion and surface marker expression.
美天旎小鼠CD4 (L3T4) MicroBeads微珠產(chǎn)品英文描述：
Mouse CD4 (L3T4) MicroBeads were developed for positive selection or depletion of mouse T helper cells from single-cell suspensions of lymphoid and non-lymphoid tissues or from peripheral blood.
The CD4 antigen is expressed on most thymocytes and mature T helper cells, and at lower levels on a subpopulation of dendritic cells. CD4 acts as an accessory molecule in the recognition of MHC class II/peptide complexes by the TCR heterodimer on CD4+ T helper cells. The CD4 antigen is expressed on approximately 90% of thymocytes, 25% of splenocytes, and 55% of lymph node cells.
